研究業績
原著論文・英文総説
Onishi T, Okayama H, Kitano H, Higashi K, Nakagawa N, Nonaka M, Oka S, Morise J.
UDP-glucuronic acid availability underlies sex difference in renal expression of nonsulfated Human Natural Killer-1 (HNK-1) glycans.
PLOS One, 20, e0335730, 2025.
DOI: https://doi.org/10.1016/j.isci.2025.113229.
Nihashi A, Nakagawa N, Sato T, Yamamoto M, Wang L, Ajima R, Saga Y, Yoshimura Y, Kanemaki MT, Iwasato T.
Inducible NMDA receptor knockdown reveals a maintenance phase in dendritic refinement of barrel cortex neurons.
iScience, 28, 113229, 2025.
DOI: https://doi.org/10.1016/j.isci.2025.113229.
Nakagawa N.
The neuronal Golgi in neural circuit formation and reorganization. (Review)
Frontiers in Neural Circuits, 18, 1504422, 2024.
DOI: 10.3389/fncir.2024.1504422
Nakagawa N^, Iwasato T^.（co-corresponding author^）
Activity-dependent dendrite patterning in the postnatal barrel cortex. (Review)
Frontiers in Neural Circuits, 18, 1409993, 2024.
DOI: 10.3389/fncir.2024.1409993
Nakagawa N^, Iwasato T^.（co-corresponding author^）
Golgi polarity shift instructs dendritic refinement in the neonatal cortex by mediating NMDA receptor signaling.
Cell Reports, 42, 112843, 2023.
DOI: https://doi.org/10.1016/j.celrep.2023.112843.
Nakagawa N^, Plestant C, Yabuno-Nakagawa K, Li J, Lee J, Huang CW, Lee A, Krupa O, Adhikari A, Thompson S, Rhynes T, Arevalo V, Stein JL, Molnár Z, Badache A, Anton ES^.（co-corresponding author^）
Memo1 mediated tiling of radial glial cells facilitates cerebral cortical development.
Neuron, 103, 836-852, 2019.
DOI: https://doi.org/10.1016/j.neuron.2019.05.049
Nakagawa N*, Li J*, Yabuno-Nakagawa K, Eom TY, Cowles M, Mapp T, Taylor R, Anton ES.（co-first author*）
APC sets the Wnt tone necessary for cerebral cortical progenitor development.
Genes and Development, 31, 1679-1692, 2017.
DOI: https://doi.org/10.1101/gad.302679.117
Onorati M, Li Z, Liu F, Sousa AMM, Nakagawa N, Li M, Dell’Anno MT, Gulden FO, Pochareddy S, Tebbenkamp ATN, Han W, Pletikos M, Gao T, Zhu Y, Bichsel C, Varela L, Szigeti-Buck K, Lisgo S, Zhang Y, Testen A, Gao XB, Mlakar J, Popovic M, Flamand M, Strittmatter SM, Kaczmarek LK, Anton ES, Horvath TL, Lindenbach BD, Sestan N.
Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia.
Cell Reports, 16, 2576-2592, 2016.
DOI: https://doi.org/10.1016/j.celrep.2016.08.038
Nakagawa N, Yagi H, Kato K, Takematsu H, Oka S.
Ectopic clustering of Cajal-Retzius and subplate cells is an initial pathological feature in Pomgnt2-knockout mice, a model of dystroglycanopathy.
Scientific Reports, 5, 11163, 2015.
DOI: https://doi.org/10.1038/srep11163
Yaji S, Manya H, Nakagawa N, Takematsu H, Endo T, Kannagi R, Yoshihara T, Asano M, Oka S.
Major glycan structure underlying expression of the Lewis X epitope in the developing brain is O-mannose-linked glycans on phosphacan/RPTPβ.
Glycobiology, 25, 376-385, 2015.
DOI: https://doi.org/10.1093/glycob/cwu118
Yagi H*, Nakagawa N*, Saito T, Kiyonari H, Abe T, Toda T, Wu SW, Khoo KH, Oka S, Kato K.（co-first author*）
AGO61-dependent GlcNAc modification primes the formation of functional glycans on α-dystroglycan.
Scientific Reports, 3, 3288, 2013.
DOI: https://doi.org/10.1038/srep03288
Nakagawa N, Takematsu H, Oka S.
HNK-1 sulfotransferase-dependent sulfation regulating laminin-binding glycans occurs in the post-phosphoryl moiety on α-dystroglycan.
Glycobiology, 23, 1066-1074, 2013.
DOI: https://doi.org/10.1093/glycob/cwt043
Nakagawa N, Manya H, Toda T, Endo T, Oka S.
Human natural killer-1 sulfotransferase (HNK-1ST)-induced sulfate transfer regulates laminin-binding glycans on α-dystroglycan.
The Journal of Biological Chemistry, 287, 30823-30832, 2012.
DOI: https://doi.org/10.1074/jbc.M112.363036
Kouno T, Kizuka Y, Nakagawa N, Yoshihara T, Asano M, Oka S.
Specific enzyme complex of beta-1,4-galactosyltransferase-II and glucuronyltransferase-P facilitates biosynthesis of N-linked human natural killer-1 (HNK-1) carbohydrate.
The Journal of Biological Chemistry, 286, 31337-31346, 2011.
DOI: https://doi.org/10.1074/jbc.M111.233353
Nakagawa N, Izumikawa T, Kitagawa H, Oka S.
Sulfation of glucuronic acid in the linkage tetrasaccharide by HNK-1 sulfotransferase is an inhibitory signal for the expression of a chondroitin sulfate chain on thrombomodulin.
Biochemical and Biophysical Research Communications, 415, 109-113, 2011.
DOI: https://doi.org/10.1016/j.bbrc.2011.10.023
著書・日本語総説
中川直樹、岡 昌吾
ジストログリカン糖鎖の生合成機構と大脳皮質形成における役割
生化学、第88巻第4号、pp. 488-491、2016.
Nakagawa N, Oka S.
HNK-1 Glyco-epitope: COMPLEX Machinery for Biosynthesis. (Book Chapter)
N. Taniguchi et al. (eds.), Glycoscience: Biology and Medicine (Springer, Tokyo), 543-549, 2015.